C. Donawho: search on Z-Library

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1

Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer

Penning, Thomas D., Zhu, Gui-Dong, Gandhi, Viraj B., Gong, Jianchun, Liu, Xuesong, Shi, Yan, Klinghofer, Vered, Johnson, Eric F., Donawho, Cherrie K., Frost, David J.

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 221 KB

english, 2009

2

Characterization of ABT-806, a Humanized Tumor-Specific Anti-EGFR Monoclonal Antibody

Reilly, E. B., Phillips, A. C., Buchanan, F. G., Kingsbury, G., Zhang, Y., Meulbroek, J. A., Cole, T. B., DeVries, P. J., Falls, H. D., Beam, C., Gu, J., Digiammarino, E. L., Palma, J. P., Donawho, C.

Journal:

Molecular Cancer Therapeutics

Year:

2015

Language:

english

File:

PDF, 1003 KB

english, 2015

3

Specific immunotherapy against occult cancer metastases

Weixin Lu, Zhongyun Dong, Cherrie Donawho, Isaiah J. Fidler

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 892 KB

english, 2002

4

An enzyme-linked immunosorbent poly(ADP-ribose) polymerase biomarker assay for clinical trials of PARP inhibitors

Xuesong Liu, Joann Palma, Robert Kinders, Yan Shi, Cherrie Donawho, Paul A Ellis, Luis E Rodriguez, Milagros Colon-Lopez, Mary Saltarelli, David LeBlond, C Thomas Lin, David J. Frost, Yan Luo, Vincent

Journal:

Analytical Biochemistry

Year:

2008

Language:

english

File:

PDF, 381 KB

english, 2008

5

Synthesis and SAR of novel, potent and orally bioavailable benzimidazole inhibitors of poly(ADP-ribose) polymerase (PARP) with a quaternary methylene-amino substituent

Gui-Dong Zhu, Viraj B. Gandhi, Jianchun Gong, Sheela Thomas, Yan Luo, Xuesong Liu, Yan Shi, Vered Klinghofer, Eric F. Johnson, David Frost, Cherrie Donawho, Ken Jarvis, Jennifer Bouska, Kennan C. Mars

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 208 KB

english, 2008

6

Molecular Regulation of UVB-Induced Cutaneous Angiogenesis

Bielenberg, Diane R, Bucana, Corazon D, Sanchez, Ricardo, Donawho, Cherrie K, Kripke, Margaret L, Fidler, Isaiah J

Journal:

The Journal of Investigative Dermatology

Year:

1998

Language:

english

File:

PDF, 1.08 MB

english, 1998

7

Photoimmunology of experimental melanoma

Cherrie K. Donawho, Margaret L. Kripke

Journal:

Cancer and Metastasis Reviews

Year:

1991

Language:

english

File:

PDF, 931 KB

english, 1991

8

Analysis of the Protective Effect of Different Sunscreens on Ultraviolet Radiation-Induced Local and Systemic Suppression of Contact Hypersensitivity and Inflammatory Responses in Mice.

Wolf, Peter, Donawho, Cherrie K., Kripke, Margaret L.

Journal:

The Journal of Investigative Dermatology

Year:

1993

File:

PDF, 3.53 MB

1993

9

Lack of correlation between UV-induced enhancement of melanoma development and local suppression of contact hypersensitivity

Cherrie K. Donawho, Margaret L. Kripke

Journal:

Experimental Dermatology

Year:

1992

Language:

english

File:

PDF, 5.84 MB

english, 1992

10

Evidence for the causal role of endogenous interferon-α/β in the regulation of angiogenesis, tumorigenicity, and metastasis of cutaneous neoplasms

Marya F. McCarty, Diane Bielenberg, Cherrie Donawho, Corazon D. Bucana, Isaiah J. Fidler

Journal:

Clinical and Experimental Metastasis

Year:

2002

Language:

english

File:

PDF, 133 KB

english, 2002

11

Induction of Primary Cutaneous Melanomas in C3H Mice by Combined Treatment with Ultraviolet Radiation, Ethanol and Aloe Emodin

Faith M. Strickland, H. Konrad Muller, L. Clifton Stephens, Corazon D. Bucana, Cherrie K. Donawho, Yan Sun, Ronald P. Pelley

Journal:

Photochemistry and Photobiology

Year:

2000

Language:

english

File:

PDF, 237 KB

english, 2000

12

Reversal of oncogene transformation and suppression of tumor growth by the novel IGF1R kinase inhibitor A-928605

William N Pappano, Paul M Jung, Jonathan A Meulbroek, Yi-Chun Wang, Robert D Hubbard, Qian Zhang, Meagan M Grudzien, Niru B Soni, Eric F Johnson, George S Sheppard, Cherrie Donawho, Fritz G Buchanan,

Journal:

Year:

2009

Language:

english

File:

PDF, 1.03 MB

english, 2009

13

Discovery and SAR of orally efficacious tetrahydropyridopyridazinone PARP inhibitors for the treatment of cancer

Gui-Dong Zhu, Jianchun Gong, Viraj B. Gandhi, Xuesong Liu, Yan Shi, Eric F. Johnson, Cherrie K. Donawho, Paul A Ellis, Jennifer J. Bouska, Donald J. Osterling, Amanda M. Olson, Chang Park, Yan Luo, Al

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.40 MB

english, 2012

14

Pharmacodynamic Evaluation of Irinotecan Therapy by FDG and FLT PET/CT Imaging in a Colorectal Cancer Xenograft Model

Sarah R. Mudd, Kimberley D. Holich, Martin J. Voorbach, Todd B. Cole, David R. Reuter, Paul Tapang, Gail Bukofzer, Arunava Chakravartty, Cherrie K. Donawho, Joann P. Palma, Gerard B. Fox, Mark Day, Ya

Journal:

Molecular Imaging and Biology

Year:

2012

Language:

english

File:

PDF, 507 KB

english, 2012

15

555 POSTER The PARP inhibitor, ABT-888 overcomes resistance in temozolomide refractory breast and prostate xenograft tumors implanted in metastatic sites in vivo

J. Palma, L. Rodriguez, Y.W. Wang, G. Bukofzer, J. Hickson, T. Penning, V. Giranda, S. Rosenberg, D. Frost, C. Donawho

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 59 KB

english, 2008

16

Comprehensive Medicinal Chemistry II || Principles of Chemotherapy and Pharmacology

Year:

2007

Language:

english

File:

PDF, 239 KB

english, 2007

17

Optimization of Phenyl-Substituted Benzimidazole Carboxamide Poly(ADP-Ribose) Polymerase Inhibitors: Identification of ( S )-2-(2-Fluoro-4-(pyrrolidin-2-yl)phenyl)-1 H -benzimidazole-4-carboxamide (A-966492), a Highly Potent and Efficacious Inhibitor

Penning, Thomas D., Zhu, Gui-Dong, Gong, Jianchun, Thomas, Sheela, Gandhi, Viraj B., Liu, Xuesong, Shi, Yan, Klinghofer, Vered, Johnson, Eric F., Park, Chang H., Fry, Elizabeth H., Donawho, Cherrie K.

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 2.92 MB

english, 2010

18

Immunologic factors in melanoma

Donawho, Cherrie K., Kripke, Margaret L.

Journal:

Clinics in Dermatology

Year:

1992

Language:

english

File:

PDF, 746 KB

english, 1992

19

246 PARP inhibitors trap PARP1 onto damaged DNA via catalytic inhibition and not by an allosteric mechanism

Hopkins, T., Solomon, L., Shi, Y., Rodriguez, L., Donawho, C., DiGiammarino, E., Panchal, S., Olson, A., Stolarik, D., Osterling, D., Gao, W., Johnson, E., Maag, D.

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 75 KB

english, 2014

20

Correlation of tumor growth suppression and methionine aminopetidase-2 activity blockade using an orally active inhibitor

Wang, J., Tucker, L. A., Stavropoulos, J., Zhang, Q., Wang, Y.-C., Bukofzer, G., Niquette, A., Meulbroek, J. A., Barnes, D. M., Shen, J., Bouska, J., Donawho, C., Sheppard, G. S., Bell, R. L.

Journal:

Proceedings of the National Academy of Sciences

Year:

2008

Language:

english

File:

PDF, 815 KB

english, 2008

21

ABT-888, an Orally Active Poly(ADP-Ribose) Polymerase Inhibitor that Potentiates DNA-Damaging Agents in Preclinical Tumor Models

Donawho, C. K., Luo, Y., Luo, Y., Penning, T. D., Bauch, J. L., Bouska, J. J., Bontcheva-Diaz, V. D., Cox, B. F., DeWeese, T. L., Dillehay, L. E., Ferguson, D. C., Ghoreishi-Haack, N. S., Grimm, D. R.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 464 KB

english, 2007

22

Response

kRIPKE, M. L., DONAWHO, C., WOLF, P.

Journal:

JNCI Journal of the National Cancer Institute

Year:

1994

Language:

english

File:

PDF, 220 KB

english, 1994

23

Potentiation of Temozolomide Cytotoxicity by Poly(ADP)Ribose Polymerase Inhibitor ABT-888 Requires a Conversion of Single-Stranded DNA Damages to Double-Stranded DNA Breaks

Liu, X., Shi, Y., Guan, R., Donawho, C., Luo, Y., Palma, J., Zhu, G.-d., Johnson, E. F., Rodriguez, L. E., Ghoreishi-Haack, N., Jarvis, K., Hradil, V. P., Colon-Lopez, M., Cox, B. F., Klinghofer, V.,

Journal:

Molecular Cancer Research

Year:

2008

Language:

english

File:

PDF, 627 KB

english, 2008

24

Effect of Sunscreens on UV Radiation-Induced Enhancement of Melanoma Growth in Mice

Wolf, P., Donawho, C. K., Kripke, M. L.

Journal:

JNCI Journal of the National Cancer Institute

Year:

1994

Language:

english

File:

PDF, 771 KB

english, 1994

25

Iniparib Nonselectively Modifies Cysteine-Containing Proteins in Tumor Cells and Is Not a Bona Fide PARP Inhibitor

Liu, X., Shi, Y., Maag, D. X., Palma, J. P., Patterson, M. J., Ellis, P. A., Surber, B. W., Ready, D. B., Soni, N. B., Ladror, U. S., Xu, A. J., Iyer, R., Harlan, J. E., Solomon, L. R., Donawho, C. K.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 657 KB

english, 2012

26

Induction of Primary Cutaneous Melanomas in C3H Mice by Combined Treatment with Ultraviolet Radiation, Ethanol and Aloe Emodin¶

Strickland, Faith M., Muller, H. Konrad, Stephens, L. Clifton, Bucana, Corazon D., Donawho, Cherrie K., Sun, Yan, Pelley, Ronald P.

Journal:

Photochemistry and Photobiology

Year:

2000

Language:

english

File:

PDF, 246 KB

english, 2000

27

Identification of genes that confer tumor cell resistance to the Aurora B kinase inhibitor, AZD1152

Guo, J, Anderson, M G, Tapang, P, Palma, J P, Rodriguez, L E, Niquette, A, Li, J, Bouska, J J, Wang, G, Semizarov, D, Albert, D H, Donawho, C K, Glaser, K B, Shah, O J

Journal:

The Pharmacogenomics Journal

Year:

2009

Language:

english

File:

PDF, 858 KB

english, 2009

28

Mechanistic Dissection of PARP1 Trapping and the Impact on in vivo Tolerability and Efficacy of PARP Inhibitors

Hopkins, T. A., Shi, Y., Rodriguez, L. E., Solomon, L. R., Donawho, C. K., Digiammarino, E. L., Panchal, S. C., Wilsbacher, J. L., Gao, W., Olson, A. M., Stolarik, D. F., Osterling, D. J., Johnson, E.

Journal:

Molecular Cancer Research

Year:

2015

Language:

english

File:

PDF, 2.68 MB

english, 2015

29

Sunburn, sunscreen, and melanoma

Donawho, Cherrie, Wolf, Peter

Journal:

Current Opinion in Oncology

Year:

1996

File:

PDF, 665 KB

1996

30

Enhanced development of murine melanoma in UV-irradiated skin: UV dose response, waveband dependence, and relation to inflammation

Donawho, C K, Wolf, P, Kripke, M L

Journal:

Melanoma Research

Year:

1994

File:

PDF, 758 KB

1994

31

Persistence of immunogenic pulmonary metastases in the presence of protective tumor immunity in a murine melanoma model

Donawho, C K, Pride, M W, Bucana, C D, Kripke, M L

Journal:

Melanoma Research

Year:

1997

File:

PDF, 223 KB

1997

32

Immunobiology of Primary Murine Melanomas

Donawho, Cherrie, Evans, Roger, Kripke, Margaret L.

Journal:

Journal of Immunotherapy

Year:

1992

File:

PDF, 663 KB

1992

33

Differential effects of sunscreens on UV-induced inflammation, histopathologic alterations, and enhancement of melanoma growth

Wolf, P., Donawho, C. K., Kripke, M. L.

Journal:

Melanoma Research

Year:

1993

File:

PDF, 209 KB

1993

34

Preclinical characterization of BET family bromodomain inhibitor ABBV-075 suggests combination therapeutic strategies

Bui, Mai H., Lin, Xiaoyu, Albert, Daniel H., Li, Leiming, Lam, Lloyd T, Faivre, Emily J., Warder, Scott, Huang, Xiaoli, Wilcox, Denise, Donawho, Cherrie K., Sheppard, George S, Wang, Le, Fidanze, Stev

Journal:

Cancer Research

Year:

2017

Language:

english

File:

PDF, 4.92 MB

english, 2017

35

Potent and conditional redirected T cell killing of tumor cells using Half DVD-Ig

Bardwell, Philip D., Staron, Matthew M., Liu, Junjian, Tao, Qingfeng, Scesney, Susanne, Bukofzer, Gail, Rodriguez, Luis E., Choi, Chee-Ho, Wang, Jennifer, Chang, Qing, Dong, Feng, Donawho, Cherrie, Wa

Journal:

Year:

2017

Language:

english

File:

PDF, 762 KB

english, 2017

36

PARP1 trapping by PARP inhibitors drives cytotoxicity both in cancer cells and healthy bone marrow

Hopkins, Todd A, Ainsworth, William B, Ellis, Paul A, Donawho, Cherrie K, DiGiammarino, Enrico L., Panchal, Sanjay C., Abraham, Vivek C., Algire, Mikkel A, Shi, Yan, Olson, Amanda M., Johnson, Eric F.

Journal:

Molecular Cancer Research

Year:

2018

Language:

english

File:

PDF, 1.38 MB

english, 2018

37

Empowering therapeutic antibodies with IFN-α for cancer immunotherapy

Guo, Jun, Xiao, Yu, Iyer, Ramesh, Lu, Xin, Lake, Marc, Ladror, Uri, Harlan, John, Samanta, Tanushree, Tomlinson, Medha, Bukofzer, Gail, Donawho, Cherrie, Shoemaker, Alex, Huang, Tzu-Hsuan, Najbauer, J

Journal:

Year:

2019

Language:

english

File:

PDF, 1.38 MB

english, 2019

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